Dr. Pliss holds a Ph.D. degree in Cellular and Molecular Biology from the Charles University, Prague, Czech Republic (2001).

In 2007 he joined the faculty of the Institute for Lasers, Photonics and Biophotonics (ILPB) at University at Buffalo, SUNY.

Artem’s multidisciplinary research is on the interface of cell science, biophotonics and bioengineering. He investigates cellular physiology using quantitative optical approaches including conventional, confocal, and multiphoton fluorescence microscopy, Fluorescence Lifetime Imaging (FLIM), Second Harmonic Generation (SHG) imaging and micro-Raman spectroscopy (BCAbox). This research is focused on the molecular environment in vital cellular organelles and its transformations throughout cellular growth, disease progression or drug-cell interactions. Artem is also very interested in development and applications of advanced biophotonics and nanophotonics technology for modern biomedical research.

Selected Recent Publications:

1. RR Schmitt, SD Mahajan, A Pliss, PN Prasad. Small molecule based EGFR targeting of biodegradable nanoparticles containing temozolomide and Cy5 dye for greatly enhanced image-guided glioblastoma therapy. Nanomedicine: Nanotechnology, Biology and Medicine 41, 102513 (2022)
2. AN Kuzmin, A Pliss, PN Prasad. Methods for lipid measurement in cells. US Patent 11,262,309 (2022)
3. A Pliss, AN Kuzmin, PN Prasad, SD Mahajan. Mitochondrial Dysfunction: A Prelude to Neuropathogenesis of SARS-CoV-2. ACS chemical neuroscience, 13, 308–312 (2022)
4. SM Levchenko, A Pliss, X Peng, PN Prasad, J Qu. Fluorescence lifetime imaging for studying DNA compaction and gene activities. Light: Science & Applications 10, 1-11 (2021)
5. A Pliss, AN Kuzmin, A Lita, R Kumar, O Celiku, GE Atilla-Gokcumen, O Gokcumen, D. Chandra, M. Larion, P.N Prasad. A Single-Organelle Optical Omics Platform for Cell Science and Biomarker Discovery. Analytical chemistry 93, 8281-8290 (2021)
6. A Lita, A Pliss, A Kuzmin, T Yamasaki, L Zhang, T Dowdy, C Burks. IDH1 mutations induce organelle defects via dysregulated phospholipids. Nature communications 12, 1-16 (2021)
7. J Wu, W Dong, Z Zhang, J Liu, M Akioma, J Liu, Y Liu, A Pliss, X Zhang, P. Luan. Emerging two-dimensional materials-based diagnosis of neurodegenerative diseases: Status and challenges. Nano Today 40, 101284 (2021)