In the Brain, "ORMOSIL" Nanoparticles Hold Promise as a Potential Vehicle for Drug Delivery
BUFFALO, N.Y. -- In the images of fruit flies, clusters of neurons are all lit up, forming a brightly glowing network of highways within the brain.
It's exactly what University at Buffalo researcher Shermali Gunawardena was hoping to see: It meant that ORMOSIL, a novel class of nanoparticles, had successfully penetrated the insects' brains. And even after long-term exposure, the cells and the flies themselves remained unharmed.
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Nigeria's National Universities Commission Partners with UB's Institute for Lasers, Photonics and Biophotonics to Build Nanomedicine Research Capacity
BUFFALO, N.Y. -- The National Universities Commission of Nigeria has selected the University at Buffalo's Institute for Lasers, Photonics and Biophotonics as its partner to form the Nigerian American Nanomedicine Organization, which will establish Joint Research Centers in Nigeria and at ILPB.
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How Do Cells Die? Biophotonic Tools Reveal Real-Time Dynamics in Living Color
New method can facilitate customized molecular medicine
In research featured on the cover of the current issue of Proceedings of the National Academy of Sciences, The Institute for Lasers, Photonics and Bio-photonics scientists have developed a biophotonic imaging approach capable of monitoring in real-time the transformations that cellular macromolecules undergo during programmed cell death.
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To Attack H1N1, other Flu Viruses, Gold Nanorods Deliver Potent Payload
Joint research by UB and CDC could lead to new generation of antiviral medicines
Future pandemics of seasonal flu, H1N1 and other drug-resistant viruses may be thwarted by a potent, immune-boosting payload that is effectively delivered to cells by gold nanorods, report scientists at the University at Buffalo and the U.S. Centers for Disease Control and Prevention. The work is published in the current issue of the Proceedings of the National Academy of Sciences.
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To Fight Drug Addiction, UB Researchers Target the Brain with Nanoparticles
Scientists in UB's Institute for Lasers, Photonics and Biophotonics and UB's Department of Medicine have developed a stable nanoparticle that delivers short RNA molecules in the brain to "silence" or turn off a gene that plays a critical role in many kinds of drug addiction.
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Nanotech Invention May Be Golden Bullet for Controlling Drug Addiction
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Nanobots in the Brain
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An siRNA-gold nanorod complex that can turn off a gene that controls addiction might form the basis of a novel drug-addiction treatment
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Study hints at new addiction therapy
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Nanobiotix Reports 'Proof of Concept' for Its Nanoparticles in Treating Glioblastoma Multiforme (Brain Cancer)
Preclinical results demonstrate that the Company's nanoparticles-nanoPDT- selectively target tumor tissues and destroy them after activation by a laser.
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Nanophotonics Comes to China By Rachel Won
Nature Photonics, September 2007, Vol.1, No.9, page 498
The first OSA topical meeting in China was dedicated to optics on the nanoscale. Experts from all over the world gathered in Hangzhou and heard how this emerging technology could help healthcare, communications and energy generation.
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Lighting the Patterns of Liquid Crystal Molecular Orientations with CARS Microscopy
In the latest issue of Applied Physics Letters, a new approach to imaging of director fields in liquid crystals is reported by a collaborative research team from the University at Buffalo and the University of Colorado at Boulder. Kachynski, Kuzmin, Prasad and Smalyukh report the 3-D imaging of LC director structures using coherent anti-Stokes Raman scattering (CARS) microscopy. This method utilizes active vibrational Raman scattering to generate contrast signal and does not require doping the liquid crystal with dyes. It offers fast image acquisition, chemical selectivity and bond-orientation specificity that are all superior to that of other techniques.
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Hybrid Nanoparticles for Multimodal Medical Imaging
Since X-rays were discovered more than a century ago, triggering a revolution in medical imaging, clinicians have sought more powerful ways to "see" into the human body.
Now, with a $1.1 million grant from the John R. Oishei Foundation, researchers in the University at Buffalo's Institute for Lasers, Photonics and Biophotonics are turning their expertise in nanomedicine to the development of new, nanoparticle-based multi-probe systems, launching a new generation of medical imaging. The grant will fund research in which two or more medical imaging techniques are combined to provide complementary information.
Part of a new field called nanobiotechnology, the UB scientists are designing these nanoparticle systems to contain multiple contrast agents for different imaging medical techniques.
The goal is to diagnose cancer and other diseases in their earliest stages by providing far more comprehensive data to clinicians.
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Magnetic Field Acts as "Remote Control" to Deliver Nanomedicine
A nanoparticle-based drug delivery concept in which an applied magnetic field directs the accumulation in tumor cells of custom-designed, drug-filled nanocarriers has been demonstrated by University at Buffalo researchers.
The new approach, recently published in Molecular Pharmaceutics, may lead to treatments that exploit the advantages of photodynamic therapy (PDT) and that have the potential to reduce drug accumulation in normal tissues.
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Top University to Award Prasad Its Highest Honor
Zhejiang University (ZJU), one of China's top research universities, traditionally bestows its most prestigious award, the honorary professorship, on Nobel Laureates and its honorary doctorate on world leaders.
Past recipients include Nobel laureates in physics, such as David Gross and T.D. Lee, and Nobel laureates in economics, such as James A. Mirrlees, Robert Mundell and Robert W. Fogel. World leaders, such as Kofi Anan, secretary general of the United Nations, have been recipients as well.
This year, for the first time, ZJU is awarding the honorary professorship not to a world leader or to a Nobel laureate, but to a University at Buffalo scientist who has earned a global reputation as a leader in the fields of photonics, biophotonics and nanophotonics, as well as a champion of world-class scientific research in developing countries.
This fall, Paras N. Prasad, Ph.D., SUNY Distinguished Professor in the Department of Chemistry at UB and executive director of its Institute for Lasers, Photonics and Biophotonics, will travel to China to receive the honorary professorship in a dedication ceremony at ZJU
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Prasad Named One of World's Top 50 in Science
Paras N. Prasad, Ph.D., SUNY Distinguished Professor in the Department of Chemistry at the University at Buffalo, has been named one of the Scientific American 50, the prestigious magazine's annual list of "outstanding acts of leadership in science and technology from the past year."
Prasad was selected for his research using customized nanoparticles developed by him and his colleagues to achieve gene therapy, avoiding the need to rely on potentially toxic viruses as vectors.
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