News

UB helping AAU, U.S. engage Indian partners in advanced research

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An Interactive International Workshop on: Advances in Materials, Photonics and Biotechnology to Impact Energy, Healthcare, and the Environment (August 26-27, 2022, at the University at Buffalo, Buffalo, New York, USA)

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An Interactive University at Buffalo – Indian Institutes of Technology US-Indo Workshop on Design, synthesis, and data-driven discovery of nanomaterials for electronics, photonics, and biotechnology (May 16-18, 2022 at the University at Buffalo)

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DARPA Proposal “Bioengineered microbial synthesis of rare earth containing nanoparticles for photon conversion” (SN-22-02-Bio-INC-FP-004) has been selected for negotiation for a potential award

UB has been selected by the Department of Defense (DoD) to lead a $7.5 million project to develop new concepts for precision testing of important qualities of semiconductor chips

“Our ambitious MURI project focuses on testing the structure, function, operation and security of the integrated circuits that comprise semiconductor chips,” says UB researcher Paras Prasad, the project’s principal investigator.
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Prof. Paras Prasad is the recipient of the 2021 IEEE Photonics Society William Streifer Scientific Achievement Award

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Prof. Paras Prasad has been selected to receive the 2018 Peter Debye Award in Physical Chemistry from the American Chemical Society

Prof. Paras Prasad has been selected to receive the 2018 Peter Debye Award in Physical Chemistry from the American Chemical Society.This national ACS award recognizes outstanding research accomplishments in theoretical and experimental physical chemistry.
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Prof. Paras Prasad has been selected to receive the 2017 Michael S. Feld Biophotonics Award from the Optical Society of America.

Prof. Paras Prasad has been selected to receive the 2017 Michael S. Feld Biophotonics Award from the Optical Society of America.

Dr. Prasad has won the 2017 IEEE Nanotechnology council pioneer award in Nanotechnology

Prof. Paras Prasad has won the 2017 IEEE Nanotechnology Council Pioneer Award in Nanotechnology. The award will be presented at the Awards Banquet at the annual IEEE Conference on Nanotechnology, July 2017 in Pittsburgh, PA.

Paras Prasad named Fellow of the National Academy of Inventors.

University at Buffalo researcher Paras Prasad, an internationally recognized expert in optics and photonics, has been named a Fellow of the National Academy of Inventors (NAI). NAI Fellow is the highest professional distinction accorded by the organization to academic researchers who have demonstrated a prolific spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on quality of life, economic development and the welfare of society..
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Dr. Prasad receives President’s Medal at University Commencement.

Distinguished University at Buffalo faculty member Dr. Paras Prasad receives the UB President’s Medal in recognition of extraordinary service to the university during the 170th annual University Commencement. The UB President’s Medal, first presented in 1990, recognizes outstanding scholarly or artistic achievements, humanitarian acts, contributions of time or treasure, exemplary leadership or any other major contribution to the development of the University at Buffalo and the quality of life in the UB community.
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Dr. Prasad receives SPIE Gold Medal.

The award, the society’s highest honor, is awarded to just one individual each year. It will be presented to Dr. Prasad this August in recognition of his “numerous, world renowned, pioneering contributions to nonlinear optics, nanophotonics and biophotonics, as well as over three decades of outstanding service to SPIE.” Dr. Prasad serves as executive director of the Institute for Lasers, Photonics and Biophotonics (ILPB). He is a SUNY Distinguished Professor in the departments of Chemistry, Physics, Medicine and Electrical Engineering.
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Onion-like layers help this efficient new nanoparticle glow.

A new, onion-like nanoparticle could open new frontiers in biomaging, solar energy harvesting and light-based security techniques. When it comes to bioimaging, near-infrared light could be used to activate the light-emitting nanoparticles deep inside the body, providing high-contrast images of areas of interest. In the realm of security, nanoparticle-infused inks could be incorporated into currency designs; such ink would be invisible to the naked eye, but glow blue when hit by a low-energy laser pulse — a trait very difficult for counterfeiters to reproduce.
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Prasad was recognized with first UB Innovation Impact Award.

The University at Buffalo will present its inaugural Innovation Impact Award to Paras Prasad, PhD, executive director of the Institute for Lasers, Photonics and Biophotonics at UB. Prasad, a SUNY Distinguished Professor and one of the world's pre-eminent scientists in nanomedicine, will be recognized for his work in developing the use of magnetic and laser-activated nanoparticles for cancer diagnosis and treatment.
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One nanoparticle, six types of medical imaging.

Using two biocompatible parts, University at Buffalo researchers and their colleagues have designed a nanoparticle that can be detected by six medical imaging techniques:

  • computed tomography (CT) scanning;
  • positron emission tomography (PET) scanning;
  • photoacoustic imaging;
  • fluorescence imaging;
  • upconversion imaging; and
  • Cerenkov luminescence imaging.
In the future, patients could receive a single injection of the nanoparticles to have all six types of imaging done.

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New Approach to Monitoring Changes in Cellular Structure May Lead to Early Detection of Cancerous Cells.

Collaborative Roswell Park/UB team uses Raman microspectroscopy to monitor drug action in single-cell assay. Researchers have developed a new approach to characterizing and monitoring changes in cellular structure. The new type of single-cell-based assay, developed by researchers at Roswell Park Cancer Institute (RPCI) and the University at Buffalo (UB), may provide a tool for detecting cancerous cells early and monitoring cell-to-cell variations in cancer progression or in response to pharmaceutical drugs.
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New technology could expand use of photodynamic therapy.

Photodynamic therapy (PDT) is an effective treatment for easily accessible tumors, such as oral and skin cancer.Doctors have used PDT to treat cancer for decades. Cancer cells absorb the drug, which is delivered to the tumor via the bloodstream or locally. Visible light then is applied to the site, which causes the drug to react with oxygen and creates a burst of free radicals that kill the tumor. Unfortunately, visible light does not penetrate tissue well. Conversely, near-infrared light penetrates tissue well but doesn't activate the drugs efficiently. To solve this problem, some researchers are developing drugs that absorb near-infrared light. This method is limited, however, because stable and efficient near-infrared absorbing photosenzitizers are notoriously difficult to synthesize. The UB-led team took a different approach, which uses the tumor's natural environment to tune the light into the necessary wavelengths.
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Prasad receives honorary doctorate from Sweden’s Royal Institute of Technology.

UB faculty member Paras Prasad has received an honorary doctorate from the Royal Institute of Technology in Sweden (KTH) for his pioneering work in areas including the use of light-based technologies to address important, global health problems. This achievement was highlighted by the Buffalo News newspaper in their "Honor Roll".
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UB spinoff Nanobiotix looks to bring cancer treatment to market.

Successful intermediate clinical trial in February generates boost in company stock price - and new funding for UB research. "It was an exciting field with a lot of great potential; at this time, it was very new, and everything needed to be done," Levy remembers, "I moved to UB because of Dr. Prasad, who proposed to me to develop my ideas in his lab. What I found there was a great place with diverse expertise in biology, physics, chemistry and medicine. This environment was quite unique 15 years ago, and clearly helped me in developing those concepts."
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In a new study, the silicon nanocrystals had no toxic effects in non-human primates

Tiny silicon crystals caused no health problems in monkeys three months after large doses were injected, marking a step forward in the quest to bring such materials into clinics as biomedical imaging agents, according to a new study. The findings, published online July 10 in the journal ACS Nano, suggest that the silicon nanocrystals, known as quantum dots, may be a safe tool for diagnostic imaging in humans. The nanocrystals absorb and emit light in the near-infrared part of the spectrum, a quality that makes them ideal for seeing deeper into tissue than traditional fluorescence-based techniques.
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New technology could help power portable devices like satellite phones and radios

According to University at Buffalo researchers,super-small particles of silicon react with water to produce hydrogen almost instantaneously. in a series of experiments, the scientists created spherical silicon particles about 10 nanometers in diameter. When combined with water, these particles reacted to form silicic acid (a nontoxic byproduct) and hydrogen - a potential source of energy for fuel cells.The reaction didn't require any light, heat or electricity, and also created hydrogen about 150 times faster than similar reactions using silicon particles 100 nanometers wide, and 1,000 times faster than bulk silicon, according to the study. The findings appeared online in Nano Letters on Jan. 14. The scientists were able to verify that the hydrogen they made was relatively pure by testing it successfully in a small fuel cell that powered a fan.
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Zimbabwe minister tours ILPB and COE in preparation for next steps in UB-Zimbabwe partnership

The Hon. Professor Heneri Dzinotyiweyi, Zimbabwe minister of science and technology development, visited Buffalo on Tuesday, Feb. 19, to tour two University at Buffalo research facilities and discuss the vision and implementation strategy for the Zimbabwe International Nanotechnology Center (ZINC) with officials at UB, its primary academic partner.Dzinotyiweyi visited the Institute for Lasers, Photonics and Biophotonics (ILPB) and then toured UB's New York State Center of Excellence in Bioinformatics and Life Sciences.
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Pioneering UB Spinoff in Nanomedicine Raises 14.2 Million Euros in IPO

While conducting postdoctoral research at UB's Institute for Lasers, Photonics and Biophotonics about a decade ago, entrepreneur Laurent Levy co-invented two nanomedicine technologies for treatment and diagnosis of cancer. These two inventions became the first intellectual property that Levy used to found Nanobiotix, a French nanomedicine firm he started in 2003. This October, Nanobiotix was listed on the NYSE Euronext market after raising 14.2 million euros ($18.1 million) in an IPO.
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Nanoparticles Glow Through Thick Layer of Tissue

An international research team has created unique photoluminescent nanoparticles that shine clearly through more than 3 centimeters of biological tissue -- a depth that makes them a promising tool for deep-tissue optical bioimaging. Though optical imaging is a robust and inexpensive technique commonly used in biomedical applications, current technologies lack the ability to look deep into tissue, the researchers said. This creates a demand for the development of new approaches that provide high-resolution, high-contrast optical bioimaging that doctors and scientists could use to identify tumors or other anomalies deep beneath the skin. The newly created nanoparticles consist of a nanocrystalline core containing thulium, sodium, ytterbium and fluorine, all encased inside a square, calcium-fluoride shell.
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UB Partners with Zimbabwe Universities to Create International Nanotechnology Center

With 14 percent of Zimbabwe's population living with HIV/AIDS and tuberculosis as a co-infection, the need for new drugs and new formulations of available treatments is crucial. To address these issues, two of the University at Buffalo's leading research centers, the Institute for Lasers, Photonics and Biophotonics (ILPB), and the New York State Center of Excellence in Bioinformatics and Life Sciences have signed on to launch the Zimbabwe International Nanotechnology Center (ZINC) -- a national nanotechnology research program -- with the University of Zimbabwe (UZ) and the Chinhoyi University of Technology (CUT).
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Shape-Shifting Materials are Goal of New Nanotechnology Project

An international research team has received a $2.9 million grant from the Air Force Office of Scientific Research to design nanomaterials whose internal structure changes shape in response to stimuli such as heat or light.
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Good News for Nanomedicine: Quantum Dots Appear Safe in Pioneering Study on Primates

A pioneering study to gauge the toxicity of quantum dots in primates has found the tiny crystals to be safe over a one-year period, a hopeful outcome for doctors and scientists seeking new ways to battle diseases like cancer through nanomedicine.
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New research may boost treatment of head and neck cancers

Researchers at the Keck School of Medicine and the State University of New York (SUNY) at Buffalo have developed a method that increases the effectiveness of radiation therapy for head and neck cancer treatment in mouse models by more than 50 percent. The study, "Gold nanorod-sphingosine kinase siRNA nanocomplexes: a novel therapeutic tool for potent radiosensitization of head and neck cancer," was led by first author Rizwan Masood, assistant professor of research in otolaryngology, and conducted in the laboratory of Uttam Sinha, associate professor of otolaryngology at the Keck School. The research was published in the journal Integrative Biology.
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In the Brain, "ORMOSIL" Nanoparticles Hold Promise as a Potential Vehicle for Drug Delivery

BUFFALO, N.Y. -- In the images of fruit flies, clusters of neurons are all lit up, forming a brightly glowing network of highways within the brain. It's exactly what University at Buffalo researcher Shermali Gunawardena was hoping to see: It meant that ORMOSIL, a novel class of nanoparticles, had successfully penetrated the insects' brains. And even after long-term exposure, the cells and the flies themselves remained unharmed.
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Nigeria's National Universities Commission Partners with UB's Institute for Lasers, Photonics and Biophotonics to Build Nanomedicine Research Capacity

BUFFALO, N.Y. -- The National Universities Commission of Nigeria has selected the University at Buffalo's Institute for Lasers, Photonics and Biophotonics as its partner to form the Nigerian American Nanomedicine Organization, which will establish Joint Research Centers in Nigeria and at ILPB.
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How Do Cells Die? Biophotonic Tools Reveal Real-Time Dynamics in Living Color

New method can facilitate customized molecular medicine

In research featured on the cover of the current issue of Proceedings of the National Academy of Sciences, The Institute for Lasers, Photonics and Bio-photonics scientists have developed a biophotonic imaging approach capable of monitoring in real-time the transformations that cellular macromolecules undergo during programmed cell death.
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